skazany na porażkę in inglese:

The enterprise was doomed to failure.

You're doomed to fail if you don't make a SWOT analysis before opening a business

You may be disappointed if you fail, but you are doomed if you don't try.

I wouldn't push him too far. You don't know what he might do. I'd say you can't be too careful. They say even a doomed mouse will bite a cat if he has no choice.

He was doomed to life-long poverty.